Originally, the simple question of "Who hates Iowa?" was asked - as though such an meth-riddled state could have natural enemies, other than the DEA, AIRBHG, or occasional rhabdomyolsis.

Naturally, this resulted in the request to have such a question automatically met with "We Hate Iowa", or, more typically, "WE HATE IOWA".

This standard response is closely associated with Fuck Clemson as an identifiying remark of the Commentariat.